Stop, Relieve and Prevent with daflon

daflon is an effective, clinically proven oral medication for the relief of Hemorrhoid symptoms. 2

What are Hemorrhoids?

Hemorrhoids are clusters of swollen veins in your anus and lower rectum, similar to varicose veins. 3

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They are a result of increased pressure on the blood vessels in your bottom and can develop inside the rectum (internal Hemorrhoids) or under the skin around the anus (external Hemorrhoids), often leading to anal discomfort, bleeding, itching or pain.

What do Hemorrhoids look like?

Do You Have Hemorrhoids?

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The symptoms of Hemorrhoids are many and varied. Typically, Hemorrhoidal swelling leads to anal discomfort and itchiness. You may also feel a bulge in your bottom, experience anal discharge, redness and inflammation, or see blood when using the toilet. If you experience any of the illustrated symptoms for the first time (or if your symptoms extend beyond a couple of days), you should consult a healthcare professional to rule out other conditions instead of self-treating right away.

Incomplete Evacuation

Bleeding

Itchy Bottom

Pain or Discomfort

Looks familiar?

daflon is a medicinal product that treats the underlying cause of Hemorrhoids for rapid relief and prevention of recurring symptoms.

Treat Your Symptoms Early

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Hemorrhoid symptoms can start off quite mildly and often resolve on their own, but this isn’t always the case. Understand the benefits of taking action to treat and prevent Hemorrhoid symptoms. 2

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External Hemorrhoids are what most people think of when they picture Hemorrhoids. Location is the only difference between the two different types of piles, but the difference in discomfort can be considerable. External Hemorrhoids form on the outside of the anus, directly on the opening where there are lots of nerve endings, which can be particularly itchy and painful.

Internal Hemorrhoids are formed deep inside the anus and are not usually visible. They can resolve without treatment, but occasionally will swell and protrude from the anus. Prolapsed Hemorrhoids are internal Hemorrhoids that have grown to the point that they protrude from the anus. Severity of internal Hemorrhoids is measured using a grading system based on how far they protrude as shown below:

Grade 1

  • Bleeding​,
  • Visible on proctoscopy​,
  • Protrusion on straining​ ,
  • No prolapse
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Grade 1

There may be bleeding, discomfort, itching, and protrusion on straining, but no evidence of prolapse. It is nonetheless essential that you treat during the first stage to avoid the worsening of symptoms.

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Grade 2

  • Bleeding​,
  • Prolapse visible at anal margin during straining​,
  • Spontaneous return when straining ends​
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Grade 2

Without treatment, your condition may worsen, leading to pain and bleeding when using the toilet. Hemorrhoids tend to prolapse when straining, but reduce when straining ceases.

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Grade 3

  • Bleeding​,
  • Visible on proctoscopy
  • Protrusion on straining
  • Prolapse requiring manual reduction
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Grade 3

When Hemorrhoids progress to Grade 3, bleeding becomes more frequent. Your piles will prolapse on straining and need to be pushed back in. You can do this by yourself, but if there is a blood clot inside the vein as well, the pain may be very severe.

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Grade 4

  • Permanent and irreducible prolapse​,
  • Bleeding​,
  • Discharge
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Grade 4

On top of previous signs and symptoms, you will have permanent piles that you cannot push back in by yourself without pain.  Surgery, in addition to venoactive treatments such as daflon, become essential.

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The main symptoms of Hemorrhoid Disease that can occur at all grades are bleeding, pain, itching and discomfort.

RISK FACTORS YOU CAN CONTROL 4

Inactivity

Constipation

Heavy lifting

Toilet habits

RISK FACTORS YOU CAN’T CONTROL 4

Age

Pregnancy

Genetics

What are the risk factors for Hemorrhoid Disease?

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Hemorrhoid Disease affect people from all walks of life at various stages in their lives. Main risk factors for Hemorrhoid Disease include chronic constipation, obesity, increasing age or pregnancy. Even though some risk factors are unavoidable, many can be reduced based on lifestyle modification.

Preventing Hemorrhoids

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Lifestyle modifications can help prevent excess pressure from building up and causing Hemorrhoids. Try incorporating some of the following advice into your daily routine to help protect against piles and their recurrence. 3

Eat High-fibre foods

Try including more high-fibre foods in your diet such as fruits, vegetables, brown rice, wholewheat pasta and wholemeal bread. These will keep your stools soft and prevent constipation (which can lead to straining and result in Hemorrhoids).

Exercise

Regular exercise will help relax muscles and increase blood flow for better healing.

Drink plenty of fluids

Drinking plenty of fluids (especially water) will help keep your stools soft and manageable.

Go when you need to

If you wait to pass a bowel movement, it can result in your stool becoming dry and harder to pass.

Try a fibre supplement

If you are struggling to get sufficient fibre through your diet, a fibre supplement can help to ensure that you are getting enough.

Avoid sitting for too long

Sitting for too long, particularly on the toilet seat, can increase the pressure on the veins around your anus, making them more susceptible to Hemorrhoids/prolapse.

Don’t strain

Straining on the toilet seat can put even more unwanted pressure on the blood vessels and aggravate an already sensitive area.

In addition to lifestyle modifications, there is a range of treatments available for easing the symptoms of Hemorrhoids, including gels, creams and suppositories.

Frequently Asked Questions

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Do I need a prescription for daflon?

daflon is an over-the-counter treatment which does not require a prescription. You may find it in a retail pharmacy or order it online depending on your location.

What is daflon used for?

daflon is an oral treatment that helps to reduce the signs and symptoms associated with Hemorrhoids, such as bleeding, anal discharge, pain, inflammation, itching, redness, discomfort, sensation of needing to pass stools and swelling.

How do I take daflon correctly for Hemorrhoids?

For daflon 500: 6 tablets a day for the first 4 days, then 4 tablets a day for the next 3 days will provide relief during acute attacks. After this, two tablets a day for two months. For use beyond two months, please consult your doctor.

How long should I take daflon for?

You should continue taking daflon 500 one tablet twice a day (or daflon 1000 one tablet once a day) for two months after an acute episode to help prevent relapse.

I take a lot of medication, can daflon be taken with other medications?

You should speak with your doctor and discuss whether daflon is safe to combine with your other medications.

What is daflon?

daflon’s active ingredient is a micronised purified flavonoid fraction (MPFF). It is composed of citrus bioflavonoids, containing 90% diosmin and 10% other flavonoids expressed as hesperidin.

What does micronised mean?

Micronised means that a substance has been broken into very small particles for more effective absorption.

How tolerated is daflon?

daflon is well tolerated, and side effects observed in trials were mild. Possible side effects include hypersensitivity/allergy, gastrointestinal discomfort, dizziness, headaches, malaise, and skin reactions.

Safety Information:

daflon 500mg Safety Information

COMPOSITION*: Micronized purified flavonoid fraction 500mg: 450mg diosmin; 50mg flavonoids expressed as hesperidin. INDICATIONS*: Treatment of organic and functional chronic venous insufficiency of the lower limbs with the following symptoms: swollen legs; pain; nocturnal cramps. Treatment of chronic hemorrhoids and acute hemorrhoidal attacks. DOSAGE AND ADMINISTRATION*: In chronic conditions: 1000mg daily. In acute hemorrhoidal attacks: the dosage can be increased up to 3000mg daily. CONTRAINDICATIONS*: Hypersensitivity to the active substance or to any of the excipients. WARNINGS*: The administration of this product for the symptomatic treatment of acute haemorrhoids does not preclude treatment for other anal conditions. If symptoms do not subside promptly, a proctological examination should be performed and the treatment should be reviewed. Excipients: sodium-free. INTERACTIONS*: None. FERTILITY*/ PREGNANCY*. BREASTFEEDING*: Avoid use of this product during pregnancy. Breast feeding is not recommended. DRIVE & USE MACHINES*. UNDESIRABLE EFFECTS*: Common: diarrhoea, dyspepsia, nausea, vomiting. Rare: dizziness, headache, malaise, rash, pruritis, urticaria. Uncommon: colitis. Frequency not known: abdominal pain, isolated face, lip, eyelid oedema. Exceptionally Quincke’s oedema. OVERDOSE*. PROPERTIES*: Vascular protector and venotonic. Daflon 500mg acts on the return vascular system: it reduces venous distensibility and venous stasis; in the microcirculation, it normalizes capillary permeability and reinforces capillary resistance. PRESENTATION*: Pack of 30 film-coated tablets of Daflon 500mg. SERVIER(S) PTE LTD 67 Ubi Avenue 1, #06-09 StarHub Green, Singapore 408942. www.servier.com

*For complete information, please refer to the Singapore Package Insert.

References:

  1. Shelygin Y, Krivokapic Z, Frolov SA, et al. Clinical acceptability study of micronized purified flavonoid fraction 1000 mg tablets versus 500 mg tablets in patients suffering acute hemorrhoidal disease. Curr Med Res Opin. 2016;32(11):1821-1826.
  2. Lohsiriwat V et al. Hemorrhoids: From basic pathophysiology to clinical Management World.
  3. Journal of Gastroenterology 2012. May 7;18 (17): 2009-2017. Chronic venous and HemORrhoidal diseases evalUation and Scientific research; Godeberge P.J Gastroenerol Hepatol. 2020;35:557-87
  4. Godeberge, Sheikh, Lohsiriwat, Jalife, Shelygin. Micronized purified flavonoid fraction in the treatment of hemorrhoidal disease. J Comp Eff Res 2021; 10(10):801-813. Misra M. et al.. British Journal of Surgery 2000, 87, 868-872.

2024